Data Explorer

Leading Causes of Death in the U.S.

Interactive mortality data filtered by age group, gender, and disease category. Source: CDC National Center for Health Statistics, National Vital Statistics System.

U.S. Mortality Data Explorer

National leading causes of death, age-adjusted rates, state-level comparison, and historical trends. Sourced from CDC NVSS, NCHS Open Data, HDPulse, and WHO.

Filter Data

Age Group

Sex

Disease Category

Total Deaths Shown

2,466,528

Filtered results · CDC NVSS 2022

Causes Shown

of 12 total

Preventable Causes

can be reduced

Viewing

All Ages

All sexes

Heart Disease

ChronicPreventable

702,678 deaths/yr212.7/100k20.1% of total

1.2%

Cancer

ChronicPreventable

608,371 deaths/yr184/100k17.4% of total

1.8%

Unintentional Injuries

InjuryPreventable

227,039 deaths/yr68.7/100k6.5% of total

2.3%

COVID-19

InfectiousPreventable

186,552 deaths/yr56.5/100k5.3% of total

45.2%

Stroke

ChronicPreventable

162,890 deaths/yr49.3/100k4.7% of total

0.3%

CLRD

ChronicPreventable

142,342 deaths/yr43.1/100k4.1% of total

3.1%

Alzheimer's Disease

Chronic

119,399 deaths/yr36.1/100k3.4% of total

2.8%

Diabetes

ChronicPreventable

103,294 deaths/yr31.3/100k3% of total

4.2%

Kidney Disease

ChronicPreventable

54,358 deaths/yr16.5/100k1.6% of total

0.5%

Influenza & Pneumonia

InfectiousPreventable

53,544 deaths/yr16.2/100k1.5% of total

8.4%

Suicide

InjuryPreventable

49,476 deaths/yr15/100k1.4% of total

2.6%

Liver Disease

ChronicPreventable

56,585 deaths/yr17.1/100k1.6% of total

3.5%

Data Sources & Reference Databases

CDC NVSS HDPulse (NIMHD)Human Mortality Database WHO GHO NHLBI Research

National data: CDC NVSS 2022 Final (deaths & percentages) and CDC Open Data API for age-adjusted rates and state comparisons (1999–2017 NCHS dataset). Age-adjusted rates per 100,000 allow valid comparison across states and time periods regardless of population age structure.